Harvard professor Robert Langdon arrives at the Guggenheim Museum Bilbao to attend the unveiling of an astonishing scientific breakthrough. The evening's host is billionaire Edmond Kirsch, a futurist whose dazzling high-tech inventions and audacious predictions have made him a controversial global figure. But before his secret can be revealed, the meticulously orchestrated evening is blown apart. With his life under threat, Langdon is forced to flee, aided by the museum's director, Ambra Vidal. If they are to beat a devious enemy to Kirsch's discovery, Langdon and Vidal must follow a perilous trail signposted only by enigmatic symbols, hidden history, and elusive modern art. At its end, they will come face-to-face with a breathtaking truth that has remained buried - until now